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Hypoxia Activated Prodrug

Showing 1 - 25 of 3,513
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Kidney Cancer, Liver Cancer Trial in Scottsdale, Rochester (hypoxia-activated prodrug TH-302, sorafenib tosylate)

Completed
  • Kidney Cancer
  • Liver Cancer
  • hypoxia-activated prodrug TH-302
  • sorafenib tosylate
  • Scottsdale, Arizona
  • +1 more
Feb 4, 2020

Solid Tumor Trial (CP-506, Carboplatin, Immune checkpoint inhibitor)

Not yet recruiting
  • Unspecified Adult Solid Tumor, Protocol Specific
  • (no location specified)
Jun 23, 2022

Recurrent T Acute Lymphoblastic Leukemia, Refractory T Acute Lymphoblastic Leukemia Trial in United States (AKR1C3-activated

Active, not recruiting
  • Recurrent T Acute Lymphoblastic Leukemia
  • Refractory T Acute Lymphoblastic Leukemia
  • AKR1C3-activated Prodrug OBI-3424
  • Birmingham, Alabama
  • +113 more
Jan 24, 2023

Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck or Skin Trial in Australia, United States (TH-4000)

Terminated
  • Metastatic Head-and-neck Squamous-cell Carcinoma
  • TH-4000 (Tarloxotinib)
  • Los Angeles, California
  • +9 more
Jan 9, 2023

Pancreatic Cancer, Colorectal Cancer, NSCLC Trial in United Kingdom (AVA6000)

Recruiting
  • Pancreatic Cancer
  • +7 more
  • Glasgow, United Kingdom
  • +5 more
Nov 24, 2022

Advanced or Metastatic Solid Tumors Trial in Birtinya, Frankston (KGX101- Cohort 1, KGX101- Cohort 2, KGX101- Cohort 3)

Not yet recruiting
  • Advanced or Metastatic Solid Tumors
  • KGX101- Cohort 1
  • +7 more
  • Birtinya, Queensland, Australia
  • +1 more
Oct 3, 2023

Prospective Primary Human Lungcancer Organoids to Predict

Recruiting
  • Lung Cancer
  • Organoids
  • Heerlen, Netherlands
  • +1 more
Feb 22, 2022

Metastatic Melanoma Trial in Canada, United States (TH-302)

Terminated
Has Results
  • Metastatic Melanoma
  • Los Angeles, California
  • +6 more
Mar 24, 2021

Hypoxemia Trial in Austin (Rebreathing-induced hypoxia, Spontaneous breathing)

Recruiting
  • Hypoxemia
  • Rebreathing-induced hypoxia
  • Spontaneous breathing
  • Austin, Texas
    The Unviersity of Texas at Austin
Jun 13, 2022

Bacterial Infections Trial (Xeruborbactam Oral Prodrug, Ceftibuten)

Not yet recruiting
  • Bacterial Infections
  • (no location specified)
Nov 27, 2023

Bacterial Infections Trial (Xeruborbactam Oral Prodrug, Ceftibuten, Xeruborbactam Oral Prodrug Placebo)

Not yet recruiting
  • Bacterial Infections
  • Xeruborbactam Oral Prodrug
  • +3 more
  • (no location specified)
Oct 6, 2023

the Relationship Between Vascular Endothelial Dysfunction and Beat-to-beat Blood Pressure Variability in Patients With OSAS

Not yet recruiting
  • the Relationship Between Vascular Endothelial Dysfunction and Beat-to-beat Blood Pressure Variability in Patients With OSAS
    • (no location specified)
    Sep 16, 2022

    Ketosis, Hypoxia Trial in Leuven, Ljubljana (Ketone ester, Placebo)

    Active, not recruiting
    • Ketosis
    • Hypoxia
    • Ketone ester
    • Placebo
    • Leuven, Belgium
    • +1 more
    Oct 19, 2023

    NSCLC Trial in Charleston (Sotorasib and Tarloxotinib)

    Recruiting
    • Non-Small Cell Lung Cancer
    • Sotorasib and Tarloxotinib
    • Charleston, South Carolina
      Hollings Cancer Center at Medical University of South Carolina
    Mar 28, 2022

    Intracranial Tumor Trial in Portland (Magnetic Resonance Imaging, Oxygen Therapy)

    Recruiting
    • Intracranial Neoplasm
    • Magnetic Resonance Imaging
    • Oxygen Therapy
    • Portland, Oregon
      OHSU Knight Cancer Institute
    Jun 6, 2023

    Normobaric Hypoxia, Hypoventilation, Normoxia Trial in Lisbon (Repeated sprint)

    Not yet recruiting
    • Normobaric Hypoxia
    • +2 more
    • Repeated sprint
    • Lisbon, Portugal
      Faculty of Human Kinetics
    Nov 10, 2023

    Hypoxia Before Radioembolization Treatment With 18F-FMISO PET

    Recruiting
    • Radioembolization
    • +3 more
    • 18F-Fluoromisonidazole PET
    • Ankara, Turkey
      Ankara University
    Sep 7, 2023

    Parkinson Disease Trial in Ann Arbor (tributyrin)

    Recruiting
    • Parkinson Disease
    • Ann Arbor, Michigan
      University of Michigan Health System Functional Neuroimaging, Co
    Sep 13, 2022

    Healthy Volunteer Trial (SPR720)

    Not yet recruiting
    • Healthy Volunteer
    • (no location specified)
    Jul 13, 2023

    Healthy Volunteers Trial in Ann Arbor (Enalapril)

    Suspended
    • Healthy Volunteers
    • Ann Arbor, Michigan
      University of Michigan
    Feb 2, 2022

    Pulse Oximeter Accuracy in Healthy Humans During Hypoxia

    Recruiting
    • Hypoxia
    • Skin Pigmentation
    • Controlled desaturation (hypoxemia)
    • San Francisco, California
      Hypoxia Lab, UCSF Department of Anesthesia and Perioperative Car
    Nov 15, 2023

    Cardiac Output, Stroke Volume Trial in Riverside (High Intensity Intervals, Moderate Exercise)

    Completed
    • Cardiac Output
    • Stroke Volume
    • High Intensity Intervals
    • Moderate Exercise
    • Riverside, California
      California Baptist University
    Apr 4, 2023

    Soft Tissue Sarcoma Trial in Toronto (Radiotherapy, Surgery)

    Not yet recruiting
    • Soft Tissue Sarcoma
    • Radiotherapy
    • Surgery
    • Toronto, Ontario, Canada
      University Health Network
    Jul 10, 2023

    Wound, Wound Infection, Wound Heal Trial in Xi'an (plasma activated saline, Routine nursing)

    Not yet recruiting
    • Wound
    • +2 more
    • plasma activated saline
    • Routine nursing
    • Xi'an, Shaanxi, China
      First Affiliated Hospital of Xian JiaotongUniversity
    Jul 5, 2023

    Cervix Cancer Trial in Toronto (18F-Fluoroazomycin Arabinoside (18F-FAZA))

    Active, not recruiting
    • Cervix Cancer
    • 18F-Fluoroazomycin Arabinoside (18F-FAZA)
    • Toronto, Ontario, Canada
      Princess Margaret Hospital
    Oct 21, 2022